Stanford researchers have found a way to predict who will suffer heart problems from a common breast-cancer drug, as well as identified an FDA-approved medication that could mitigate those side effects.
To study the effects of nicotine use in pregnant women, Stanford ChEM-H Faculty Fellow Joseph Wu and colleagues developed an "embryoid in a dish," a clump of stem cells that mimics the developing fetus.
Stanford ChEM-H Faculty Fellow Chris Garcia has uncovered a detailed structure of interferon-gamma (IFN-gamma), a signaling protein critical to the body's immune responses. This information could help scientists develop strategies to boost immune responses without inadvertently dampening them.
A team led by ChEM-H Faculty Fellow Calvin Kuo has discovered a way to invert enteroids, lab-cultured spheres that mimic intestinal tissue. The exposed inner surface provides a new platform to study how intestinal lining interacts with drugs and pathogens.
Stanford ChEM-H Faculty Fellow Justin Annes discusses the importance of collaborative, interdisciplinary research and how ChEM-H has made his research program in diabetes and hereditary endocrine disorders possible in the Stanford Department of Medicine 2019 Annual Report.