Stanford researchers have found a way to predict who will suffer heart problems from a common breast-cancer drug, as well as identified an FDA-approved medication that could mitigate those side effects.
Stanford ChEM-H Faculty Fellow Chris Garcia has uncovered a detailed structure of interferon-gamma (IFN-gamma), a signaling protein critical to the body's immune responses. This information could help scientists develop strategies to boost immune responses without inadvertently dampening them.
To study the effects of nicotine use in pregnant women, Stanford ChEM-H Faculty Fellow Joseph Wu and colleagues developed an "embryoid in a dish," a clump of stem cells that mimics the developing fetus.
A team led by ChEM-H Faculty Fellow Calvin Kuo has discovered a way to invert enteroids, lab-cultured spheres that mimic intestinal tissue. The exposed inner surface provides a new platform to study how intestinal lining interacts with drugs and pathogens.
Stanford ChEM-H Faculty Fellow Justin Annes discusses the importance of collaborative, interdisciplinary research and how ChEM-H has made his research program in diabetes and hereditary endocrine disorders possible in the Stanford Department of Medicine 2019 Annual Report.